Critical care education one page at a time. Simple, free, & open source.
Nick Mark’s OnePager guides to critical care topics.
Lactic Acidosis
#criticalCare #acidBase #shock #resuscitation
Lactate and Lactic acid are frequently used (& oft misunderstood) labs in the ICU. This OnePager reviews the physiology of why/how we produce lactic acid and breaks lactic acidosis into two categories: Impaired O2 Delivery (Type A Lactic Acidosis) and Impaired O2 clearance/utilization (Type B Lactic Acidosis). I also discuss the rare and easily missed Type D Lactic acidosis (due to bacterial production of the stereoisomer).
Current version 1.0 (originally posted 2021-01-25). Also available in 🇪🇸Spanish (JPEG), 🇩🇪 German (PDF, PNG, PPT), and 🇫🇷 French (PDF, PNG, PPT)
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Clinical use of lactate monitoring in critically ill patients, Annals of Intensive Care 2013
Lactate, a useful marker for disease mortality and severity but an unreliable marker of tissue hypoxia/hypoperfusion in critically ill patients, Acute Med Surg 2016
D-lactate in human and ruminant metabolism, J Nutrition 2005
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See Approach to Acid/Base
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Also available in 🇪🇸Spanish (JPEG)
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