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Nick Mark’s OnePager guides to critical care topics.
Pulmonary Renal Syndromes
#pulmonary #rheumatology #criticalCare #nephrology
Pulmonary Renal syndromes are both complex and potentially life threatening, making rapid and accurate diagnosis essential but challenging. This ICU OnePager reviews the pathogenesis and differential diagnosis, including ANCA vasculitis (GPA, MPA, EGPA), anti-basement membrane disease (anti-GBM), as well as other diseases that can present similarly (SLE & other rheum diseases), and infections. It also explains how diffuse alveolar hemorrhage (DAH) is diagnosed and how to interpret ANCA testing and renal pathology.
Current version 1.0 (originally posted 2021-06-04).
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Bench-to-bedside review: Pulmonary–renal syndromes – an update for the intensivist, Critical Care 2007
RAVE-ITN Study, NEJM 2010 (randomized controlled trial of rituximab vs cyclophosphamide in ANCA vasculitis)
Utility of DLCO in DAH, NEJM 1976
How ANCA Antibodies Activate Neutrophils, Clin Exp Immunol 2012
Diffuse pulmonary hemorrhage: clues to the diagnosis, Curr Probl Diagn Radiol 2014
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None… Yet!
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Current version 1.0 (originally posted 2021-06-04).
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RheumOnePagers - an amazing site for all things rheumatology related!